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Site Information |
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sITLKNktEssLLAk SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 1737602 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
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Upstream Regulation | |
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Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on TTK: | |
Effects of modification on biological processes: |
References | |
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Wang X, et al. (2014) Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression. PLoS One 9, e104723
25265012 Curated Info |
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Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546 Curated Info |
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Xu Q, et al. (2009) Regulation of kinetochore recruitment of two essential mitotic spindle checkpoint proteins by Mps1 phosphorylation. Mol Biol Cell 20, 10-20
18923149 Curated Info |
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Jelluma N, et al. (2008) Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. PLoS One 3, e2415
18545697 Curated Info |
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Kang J, Chen Y, Zhao Y, Yu H (2007) Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint. Proc Natl Acad Sci U S A 104, 20232-7
18083840 Curated Info |