Ser335
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Home > Phosphorylation Site Page: > Ser335  -  ASBT (rat)

Site Information
NDMDPMPsFQEtNKG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 453445

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , MzChA (hepatic) ( 2 )

Upstream Regulation
Treatments:
cycloheximide ( 2 ) , IL-1b ( 2 ) , MG132 ( 2 )

Downstream Regulation
Effects of modification on ASBT:
protein degradation ( 2 )

References 

1

Chothe PP, Swaan PW (2014) Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2). Biochem J 459, 301-12
24498857   Curated Info

2

Xia X, et al. (2004) Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes. J Biol Chem 279, 44931-7
15304498   Curated Info