Ser801
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Home > Phosphorylation Site Page: > Ser801  -  PKD2 (human)

Site Information
SSLPRPMsSRSFPRs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15702202

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoassay ( 1 ) , immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PRKD2 (human) ( 2 )
Kinases, in vitro:
PKACA (rat) ( 2 )
Treatments:
ATP ( 2 ) , EGF ( 2 ) , GF109203X ( 2 ) , Go_6976 ( 2 ) , Go_6983 ( 2 ) , KN-93 ( 2 ) , PKA_inhibitor ( 2 ) , PKC_inhibitor ( 2 ) , serum ( 2 ) , siRNA ( 2 ) , staurosporine ( 2 )

Downstream Regulation
Effects of modification on PKD2:
activity, induced ( 2 )
Effects of modification on biological processes:
cell cycle regulation ( 2 )

References 

1

Streets AJ, Wessely O, Peters DJ, Ong AC (2013) Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. Hum Mol Genet 22, 1924-39
23390129   Curated Info

2

Streets AJ, Needham AJ, Gill SK, Ong AC (2010) Protein Kinase D-mediated Phosphorylation of Polycystin-2 (TRPP2) Is Essential for Its Effects on Cell Growth and Calcium Channel Activity. Mol Biol Cell 21, 3853-3865
20881056   Curated Info