Tyr120
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Home > Phosphorylation Site Page: > Tyr120  -  CREB (mouse)

Site Information
ILsRRPsyRkILNDL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15409156

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 , 3 )
Disease tissue studied:
liver cancer ( 2 )
Relevant cell line - cell type - tissue:
HepG2 (hepatic) ( 2 ) , neuron ( 3 )

Downstream Regulation
Effects of modification on CREB:
phosphorylation ( 2 , 3 )
Effects of modification on biological processes:
neural plasticity ( 3 ) , transcription, inhibited ( 2 )

References 

1

Kim SH, et al. (2021) Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst-attenuation of the cyclic AMP response element binding protein. J Biol Chem 297, 100908
34171357   Curated Info

2

Montgomery MK, et al. (2020) SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control. Sci Transl Med 12
32878981   Curated Info

3

Moro A, van Woerden GM, Toonen RF, Verhage M (2020) CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles. PLoS Biol 18, e3000826
32776935   Curated Info