Arg16

Site Information
GPSVPTGrAMPSRRV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 15380427
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 )
Disease tissue studied:	colorectal cancer ( 9 ) , colorectal carcinoma ( 9 ) , lung cancer ( 4 , 5 ) , non-small cell lung cancer ( 4 , 6 , 7 ) , non-small cell lung adenocarcinoma ( 4 , 5 ) , non-small cell large cell lung carcinoma ( 4 ) , non-small cell squamous cell lung carcinoma ( 5 , 7 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , A549 (pulmonary) ( 6 ) , HCC15 (pulmonary) ( 5 ) , HCT116 (intestinal) ( 3 , 8 , 9 ) , LOU-NH91 (squamous) ( 5 ) , lung ( 4 , 5 ) , NCI-H1299 (pulmonary) ( 4 ) , NCI-H1703 (squamous) ( 5 , 7 ) , NCI-H1734 (pulmonary) ( 4 ) , NCI-H1944 (pulmonary) ( 4 ) , NCI-H2073 (pulmonary) ( 5 ) , NCI-H2342 (pulmonary) ( 5 ) , NCI-H358 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 4 ) , T lymphocyte ( 2 )

References
1	Larsen SC, et al. (2016) Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells. Sci Signal 9, rs9 27577262 Curated Info
2	Geoghegan V, et al. (2015) Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling. Nat Commun 6, 6758 25849564 Curated Info
3	Guo A, et al. (2014) Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics 13, 372-87 24129315 Curated Info
4	Rikova K (2013) CST Curation Set: 20097; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
5	Rikova K (2013) CST Curation Set: 20099; Year: 2013; Biosample/Treatment: cell line, H2342, H2073, Lou-NH91, HCC15, H1703; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
6	Rikova K (2012) CST Curation Set: 16037; Year: 2012; Biosample/Treatment: cell line, A549/iressa, gleevec, crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine (Me-R4-100) Rabbit mAb Cat#: 8015 Curated Info
7	Rikova K (2012) CST Curation Set: 16036; Year: 2012; Biosample/Treatment: cell line, H1703/gleevec; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
8	Mulhern D (2011) CST Curation Set: 13243; Year: 2011; Biosample/Treatment: cell line, HCT116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine (R*GG) (D5A12) Rabbit mAb Cat#: 8711, PTMScan(R) Mono-Methyl Arginine (D5A12) Immunoaffinity Beads Cat#: 8963 Curated Info
9	Possemato A (2010) CST Curation Set: 8861; Year: 2010; Biosample/Treatment: cell line, HCT 116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Curated Info