Thr566
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Home > Phosphorylation Site Page: > Thr566  -  PLD2 (human)

Site Information
FIQRWNFtKTTKAKy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15343400

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCD (human) ( 1 )
Kinases, in vitro:
PKCD (human) ( 1 )
Treatments:
fibronectin ( 1 )

Downstream Regulation
Effects of modification on PLD2:
intracellular localization ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Chae YC, et al. (2010) Protein Kinase C{delta}-Mediated Phosphorylation of Phospholipase D Controls Integrin-Mediated Cell Spreading. Mol Cell Biol 30, 5086-98
20733000   Curated Info

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