Ser1505

Site Information
DGFsCsssLsALsLD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 452096

Upstream Regulation
Kinases, in vitro:	CK1A (human) ( 1 ) , CK1D (human) ( 1 ) , CK1G1 (human) ( 1 )

Downstream Regulation
Effects of modification on APC:	molecular association, regulation ( 2 ) , phosphorylation ( 1 )
Induce interaction with:	CTNNB1 (human) ( 2 )

References
1	Ferrarese A, et al. (2007) Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3. Biochemistry 46, 11902-10 17910481 Curated Info
2	Tickenbrock L, et al. (2003) Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein. J Mol Biol 327, 359-67 12628243 Curated Info