Ser562
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser562  -  Afadin (mouse)

Site Information
LDsDRVssAsstAER   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15175962

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 3 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 )

Upstream Regulation
Treatments:
NAG-thiazoline ( 3 ) , okadaic_acid ( 3 ) , PUGNAc ( 3 )

References 

1

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

2

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

3

Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-8
18779572   Curated Info