Tyr1079
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Home > Phosphorylation Site Page: > Tyr1079  -  LEPR (human)

Site Information
NDKKSIYyLGVTSIK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451292

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on LEPR:
activity, induced ( 2 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Ohba S, Lanigan TM, Roessler BJ (2010) Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes. Osteoarthritis Cartilage 18, 1620-9
20868760   Curated Info

2

Gong Y, et al. (2007) The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms. J Biol Chem 282, 31019-27
17726024   Curated Info