Lys723
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Home > Ubiquitylation Site Page: > Lys723  -  SRC-3 (human)

Site Information
CGDGNVVkQEQLsPK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1505897100

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on SRC-3:
activity, induced ( 1 ) , molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
ER-alpha (human) ( 1 )

References 

1

Wu RC, Feng Q, Lonard DM, O'Malley BW (2007) SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell 129, 1125-40
17574025   Curated Info