Tyr341
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr341  -  Cbl-c (human)

Site Information
SEEQLQLyWAMDSTF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14913506

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )
Kinases, in vitro:
Src (human) ( 2 )

Downstream Regulation
Effects of modification on Cbl-c:
enzymatic activity, induced ( 2 ) , molecular association, regulation ( 2 )
Inhibit interaction with:
UBE2D2 (human) ( 2 )

References 

1

Calco GN, et al. (2014) CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains. J Biol Chem 289, 7307-19
24425877   Curated Info

2

Ryan PE, et al. (2010) The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme. J Biol Chem 285, 23687-98
20525694   Curated Info