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| Site Information |
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| IRRPRNYsVGSRPLQ SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 452046 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Downstream Regulation | |
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| Effects of modification on PFKFB2: | |
| References | |
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Mouton V, et al. (2007) Evaluation of the role of protein kinase Czeta in insulin-induced heart 6-phosphofructo-2-kinase activation. Cell Signal 19, 52-61
16829026 Curated Info |
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Deprez J, et al. (2000) Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase. Biochem J 347 Pt 1, 305-12
10727432 Curated Info |
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Bertrand L, et al. (1999) Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B. J Biol Chem 274, 30927-33
10521487 Curated Info |
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Deprez J, et al. (1997) Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J Biol Chem 272, 17269-75
9211863 Curated Info |
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