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Site Information |
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LIDENLLsPLAGEDD SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 451796 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on GR: | |
Effects of modification on biological processes: |
References | |
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Ponce-Lina R, et al. (2020) Differential Phosphorylation of the Glucocorticoid Receptor in Hippocampal Subregions Induced by Contextual Fear Conditioning Training. Front Behav Neurosci
32116592 Curated Info |
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Lee MS, et al. (2013) Antidepressant-like effects of Cortex Mori Radicis extract via bidirectional phosphorylation of glucocorticoid receptors in the hippocampus. Behav Brain Res 236, 56-61
22940457 Curated Info |
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Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012 Curated Info |
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Adzic M, et al. (2009) The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats. Int J Biochem Cell Biol 41, 2181-8
19782950 Curated Info |
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Adzic M, et al. (2009) Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain. J Endocrinol 202, 87-97
19406955 Curated Info |
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Davies L, et al. (2008) Cross talk of signaling pathways in the regulation of the glucocorticoid receptor function. Mol Endocrinol 22, 1331-44
18337589 Curated Info |
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Blind RD, Garabedian MJ (2008) Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes. J Steroid Biochem Mol Biol 109, 150-7
18304804 Curated Info |
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Szatmáry Z, Garabedian MJ, Vilcek J (2004) Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase. J Biol Chem 279, 43708-15
15292225 Curated Info |
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De Los Pinos E, Fernández De Mattos S null, Joaquin M, Tauler A (2001) Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway. Biochem J 353, 267-73
11139390 Curated Info |
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Pocuca N, et al. (1998) Using yeast to study glucocorticoid receptor phosphorylation. J Steroid Biochem Mol Biol 66, 303-18
9749836 Curated Info |
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Rogatsky I, Waase CL, Garabedian MJ (1998) Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation. J Biol Chem 273, 14315-21
9603939 Curated Info |
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Rogatsky I, Logan SK, Garabedian MJ (1998) Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase. Proc Natl Acad Sci U S A 95, 2050-5
9482836 Curated Info |
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Krstic MD, Rogatsky I, Yamamoto KR, Garabedian MJ (1997) Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor. Mol Cell Biol 17, 3947-54
9199329 Curated Info |