Ser117
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus®
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser117  -  PINX1 (human)

Site Information
sFSLEEKsKISKNRV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14823407

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Kinases, in vitro:
PLK1 (human) ( 1 )
Treatments:
GW_843682X ( 1 ) , nocodazole ( 1 )

Downstream Regulation
Effects of modification on PINX1:
protein degradation ( 1 ) , ubiquitination ( 1 )

References 

1

Wang C, et al. (2010) Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability. Eur J Cell Biol 89, 748-56
20573420   Curated Info