Thr141
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Home > Phosphorylation Site Page: > Thr141  -  PINX1 (human)

Site Information
DLSSRSKtDLDCIFG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14823403

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 2 ) , immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 2 )
Kinases, in vitro:
PLK1 (human) ( 2 )
Treatments:
GW_843682X ( 2 ) , nocodazole ( 2 )

Downstream Regulation
Effects of modification on PINX1:
protein degradation ( 2 ) , ubiquitination ( 2 )

References 

1

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info

2

Wang C, et al. (2010) Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability. Eur J Cell Biol 89, 748-56
20573420   Curated Info