Ser356
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Home > Phosphorylation Site Page: > Ser356  -  Bcr (mouse)

Site Information
SGQSSRVsPsPTTyR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447791

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 4 , 5 ) , mutation of modification site ( 6 ) , western blotting ( 6 )
Relevant cell line - cell type - tissue:
BaF3 ('B lymphocyte, precursor') [Bcr (mouse), transfection] ( 6 ) , brain ( 5 ) , kidney ( 5 ) , liver ( 1 , 4 ) , lung ( 5 )

Downstream Regulation
Effects of modification on Bcr:
enzymatic activity, inhibited ( 6 )
Effects of modification on biological processes:
cell growth, altered ( 6 )

References 

1

Robles MS, Humphrey SJ, Mann M (2017) Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. Cell Metab 25, 118-127
27818261   Curated Info

2

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

3

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

4

Wilson-Grady JT, Haas W, Gygi SP (2013) Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation. Methods 61, 277-86
23567750   Curated Info

5

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

6

Perazzona B, et al. (2008) Kinase domain mutants of Bcr enhance Bcr-Abl oncogenic effects. Oncogene 27, 2208-14
17934518   Curated Info