Ser16
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Home > O-GlcNAc Site Page: > Ser16  -  PLB (rat)

Site Information
RSAIRRAstIEMPQQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14738100

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
CHO-K1 (fibroblast) ( 1 ) , HeLa (cervical) ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Treatments:
azaserine ( 1 ) , high_glucose ( 1 ) , PUGNAc ( 1 ) , streptozotocin ( 1 )

Downstream Regulation
Effects of modification on PLB:
molecular association, regulation ( 1 )
Induce interaction with:
SERCA2 (rat) ( 1 )

References 

1

Yokoe S, et al. (2010) Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy. Glycobiology 20, 1217-26
20484118   Curated Info

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