Thr679

Site Information
RQLVRKRtLRRLLQE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 448053

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	hepatocyte ( 1 ) , liver ( 1 ) , PC-12 (chromaffin) ( 2 )

Upstream Regulation
Treatments:	bradykinin ( 2 ) , EGF ( 2 ) , methyl-beta-cyclodextrin ( 2 ) , partial_hepatectomy ( 1 ) , phorbol_ester ( 1 ) , PP2 ( 2 )

References
1	Skarpen E, et al. (2005) Altered regulation of EGF receptor signaling following a partial hepatectomy. J Cell Physiol 202, 707-16 15389569 Curated Info
2	Hur EM, et al. (2004) Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains. J Biol Chem 279, 5852-60 14630916 Curated Info