Tyr17
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Home > Phosphorylation Site Page: > Tyr17  -  NPM1 (mouse)

Site Information
sPLRPQNyLFGCELK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 14577035

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:
32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ( 2 ) , 32Dcl3 (myeloid) ( 2 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Regulatory protein:
FLT3 (mouse) ( 2 )

References 

1

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

2

Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39
19854140   Curated Info

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