Ser280

Site Information
HPsDGEtsVQPMMTK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 14572439

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Relevant cell line - cell type - tissue:	293 (epithelial) [DGCR8 (human), transfection] ( 1 ) , HeLa (cervical) ( 3 ) , Jurkat (T lymphocyte) ( 2 )

Downstream Regulation
Effects of modification on DGCR8:	protein stabilization ( 1 )

References
1	Herbert KM, et al. (2013) Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile. Cell Rep 5, 1070-81 24239349 Curated Info
2	Possemato A (2008) CST Curation Set: 5316; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info
3	Ruse CI, et al. (2008) Motif-specific sampling of phosphoproteomes. J Proteome Res 7, 2140-50 18452278 Curated Info