Tyr75
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Home > Phosphorylation Site Page: > Tyr75  -  emerin (mouse)

Site Information
AAVDSDMyDLPKkED   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451787

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , MRC5 (fibroblast) ( 1 ) , Neuro-2a (neuron) ( 2 )

Upstream Regulation
Putative in vivo kinases:
Src iso1 (mouse) ( 1 )
Treatments:
force ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell motility, induced ( 1 ) , cytoskeletal reorganization ( 1 ) , transcription, induced ( 1 )

References 

1

Guilluy C, et al. (2014) Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus. Nat Cell Biol 16, 376-81
24609268   Curated Info

2

Schlosser A, Amanchy R, Otto H (2006) Identification of tyrosine-phosphorylation sites in the nuclear membrane protein emerin. FEBS J 273, 3204-15
16857009   Curated Info

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