Ser207
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Home > Phosphorylation Site Page: > Ser207  -  prolactin (human)

Site Information
LHCLRRDsHKIDNYL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451732

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PAK2 (rat) ( 2 )

Downstream Regulation
Effects of modification on prolactin:
protein conformation ( 1 )

References 

1

Ueda EK, et al. (2009) A molecular mimic of phosphorylated prolactin (S179D PRL) secreted by eukaryotic cells has a conformation with an increased positive surface charge compared to that of unmodified prolactin. Biochemistry 48, 6887-97
19555049   Curated Info

2

Tuazon PT, Lorenson MY, Walker AM, Traugh JA (2002) p21-activated protein kinase gamma-PAK in pituitary secretory granules phosphorylates prolactin. FEBS Lett 515, 84-8
11943200   Curated Info