Ser300
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser300  -  ADRA1D (human)

Site Information
KRERGKAsEVVLRIH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1424270001

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
GRK2 (human) ( 1 ) , PKCA (human) ( 1 )
Treatments:
Go_6976 ( 1 ) , norepinephrine ( 1 ) , paroxetine ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on ADRA1D:
receptor internalization, altered ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )

References 

1

Alfonzo-Méndez MA, et al. (2018) Different phosphorylation patterns regulate α-adrenoceptor signaling and desensitization. Biochim Biophys Acta 1865, 842-854
29551601   Curated Info