Thr698
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.8.0
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr698  -  ERK3 (human)

Site Information
kSIQATLtPSAMkss   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 13830502

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 )

Upstream Regulation
Regulatory protein:
CCNA2 (human) ( 1 ) , CCNB1 (human) ( 1 ) , CCND1 (human) ( 1 ) , CCNE1 (human) ( 1 )
Putative in vivo kinases:
CDK1 (human) ( 1 )
Kinases, in vitro:
CDK1 (human) ( 1 )
Putative upstream phosphatases:
CDC14A (human) ( 1 ) , CDC14B (human) ( 1 )
Treatments:
nocodazole ( 1 ) , seliciclib ( 1 ) , SU9516 ( 1 )

Downstream Regulation
Effects of modification on ERK3:
protein stabilization ( 1 )

References 

1

Tanguay PL, Rodier G, Meloche S (2010) C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis. Biochem J 428, 103-11
20236090   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.