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Powered by Cell Signaling Technology |
| Site Information |
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| SREVFDFsQRQKDYE SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 450082 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Disease tissue studied: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Putative in vivo kinases: | |
| Kinases, in vitro: | |
| Treatments: | |
| Downstream Regulation | |
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| Effects of modification on NRF2: | |
| Effects of modification on biological processes: | |
| Induce interaction with: | |
| Inhibit interaction with: | |
| References | |
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Kim DE, et al. (2022) Plk2-mediated phosphorylation and translocalization of Nrf2 activates anti-inflammation through p53/Plk2/p21 signaling in acute kidney injury. Cell Biol Toxicol
35842499 Curated Info |
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Kaneko YS, et al. (2015) Aripiprazole increases NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells. J Neural Transm 122, 757-72
25504008 Curated Info |
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Chang WC, et al. (2015) Scopoletin Protects against Methylglyoxal-Induced Hyperglycemia and Insulin Resistance Mediated by Suppression of Advanced Glycation Endproducts (AGEs) Generation and Anti-Glycation. Molecules 20, 2786-801
25671364 Curated Info |
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Lee BH, et al. (2012) Ankaflavin: a natural novel PPARĪ³ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic Biol Med 53, 2008-16
23022408 Curated Info |
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Huang HC, Nguyen T, Pickett CB (2002) Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem 277, 42769-74
12198130 Curated Info |
