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Home > Phosphorylation Site Page: > Ser41  -  GAP43 (cow)

Site Information
AATKIQAsFRGHITR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448719

Upstream Regulation
Kinases, in vitro:
PHKG1 (human) ( 3 ) , PKCA (cow) ( 2 ) , PKCA (human) ( 1 )

Downstream Regulation
Effects of modification on GAP43:
protein processing ( 1 , 2 )



Zakharov VV, Mosevitsky MI (2007) M-calpain-mediated cleavage of GAP-43 near Ser41 is negatively regulated by protein kinase C, calmodulin and calpain-inhibiting fragment GAP-43-3. J Neurochem 101, 1539-51
17326767   Curated Info


Zakharov VV, Bogdanova MN, Mosevitsky MI (2005) Specific proteolysis of neuronal protein GAP-43 by calpain: characterization, regulation, and physiological role. Biochemistry (Mosc) 70, 897-907
16212546   Curated Info


Paudel HK, Zwiers H, Wang JH (1993) Phosphorylase kinase phosphorylates the calmodulin-binding regulatory regions of neuronal tissue-specific proteins B-50 (GAP-43) and neurogranin. J Biol Chem 268, 6207-13
8454596   Curated Info