Ser329
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Home > Phosphorylation Site Page: > Ser329  -  p47phox (mouse)

Site Information
QDtYRRNsVRFLQQR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449404

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , neutrophil ( 1 ) , neutrophil-blood ( 2 )

Upstream Regulation
Putative in vivo kinases:
MAPKAPK2 (human) ( 1 )
Kinases, in vitro:
MAPKAPK2 (human) ( 1 )
Treatments:
C5a ( 1 ) , fMLP ( 2 ) , phorbol_ester ( 2 ) , TNF ( 2 )

Downstream Regulation
Effects of modification on p47phox:
enzymatic activity, induced ( 1 ) , intracellular localization ( 1 )

References 

1

Sun L, et al. (2018) A Role for MK2 in Enhancing Neutrophil-Derived ROS Production and Aggravating Liver Ischemia/Reperfusion Injury. Front Immunol 9, 2610
30483268   Curated Info

2

Jennings RT, et al. (2014) RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness. Blood 123, 3635-45
24782506   Curated Info