Ser865

Site Information
stEVKEDsAYGsQSV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 450166

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , macrophage-peritoneum [MPRIP (mouse), homozygous knockout] ( 2 )

Downstream Regulation
Effects of modification on NFkB-p100:	molecular association, regulation ( 1 )
Induce interaction with:	TRIM55 (human) ( 1 )

References
1	Lin L, et al. (2023) TRIM55 promotes noncanonical NF-κB signaling and B cell-mediated immune responses by coordinating p100 ubiquitination and processing. Sci Signal 16, eabn5410 37816088 Curated Info
2	Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51 22942356 Curated Info