Ser219
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Home > Phosphorylation Site Page: > Ser219  -  RARA (human)

Site Information
NSSEQRVsLDIDLWD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 13373501

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Treatments:
cAMP_analog ( 1 ) , retinoic_acid ( 1 ) , urofollitropin ( 1 )

Downstream Regulation
Effects of modification on RARA:
activity, inhibited ( 1 ) , intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
RXRA (human) ( 1 )

References 

1

Santos NC, Kim KH (2010) Activity of retinoic acid receptor-alpha is directly regulated at its protein kinase A sites in response to follicle-stimulating hormone signaling. Endocrinology 151, 2361-72
20215566   Curated Info