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Site Information |
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__ArtkQtArkstGG SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 13321500 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Putative in vivo kinases: | |
Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on H3: | |
Effects of modification on biological processes: | |
Inhibit interaction with: |
Disease / Diagnostics Relevance | |
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Relevant diseases: |
References | |
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Krapivinsky G, et al. (2017) Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression. Proc Natl Acad Sci U S A 114, E7092-E7100
28784805 Curated Info |
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Pacaud R, et al. (2015) Histone H3 Phosphorylation in GBM: a New Rational to Guide the Use of Kinase Inhibitors in anti-GBM Therapy. Theranostics 5, 12-22
25553095 Curated Info |
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Cai C, et al. (2014) Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity. Cell Rep 9, 1618-27
25482560 Curated Info |
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Metzger E, et al. (2010) Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4. Nature 464, 792-6
20228790 Curated Info |
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Garske AL, et al. (2010) Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol 6, 283-90
20190764 Curated Info |