Ser115

Site Information
KQELRRKsKLVEEPI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 451519

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 ) , phosphoamino acid analysis ( 2 ) , phosphopeptide mapping ( 2 )
Relevant cell line - cell type - tissue:	CV1 (fibroblast) ( 2 ) , GH3 (epithelial) ( 2 ) , GH4T2 (pituitary cell) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Kinases, in vitro:	PKACA (rat) ( 2 )

References
1	Jean A, Gutierrez-Hartmann A, Duval DL (2010) A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit ras and estrogen stimulation of the prolactin gene promoter. Mol Endocrinol 24, 91-103 19887646 Curated Info
2	Caelles C, Hennemann H, Karin M (1995) M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding. Mol Cell Biol 15, 6694-701 8524234 Curated Info