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Powered by Cell Signaling Technology |
| Site Information |
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| RKRKRRTtISIAAKD SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 451518 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Kinases, in vitro: | |
| Treatments: | |
| Downstream Regulation | |
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| Effects of modification on GHF-1: | |
| Effects of modification on biological processes: | |
| Induce interaction with: | |
| Inhibit interaction with: | |
| References | |
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Jean A, Gutierrez-Hartmann A, Duval DL (2010) A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit ras and estrogen stimulation of the prolactin gene promoter. Mol Endocrinol 24, 91-103
19887646 Curated Info |
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Augustijn KD, et al. (2002) Structural characterization of the PIT-1/ETS-1 interaction: PIT-1 phosphorylation regulates PIT-1/ETS-1 binding. Proc Natl Acad Sci U S A 99, 12657-62
12242337 Curated Info |
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Caelles C, Hennemann H, Karin M (1995) M-phase-specific phosphorylation of the POU transcription factor GHF-1 by a cell cycle-regulated protein kinase inhibits DNA binding. Mol Cell Biol 15, 6694-701
8524234 Curated Info |
