Tyr326
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Home > Phosphorylation Site Page: > Tyr326  -  ADRB2 (human)

Site Information
SGFNPLIyCRSPDFR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451497

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 3 ) , mutation of modification site ( 3 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 3 )

Upstream Regulation
Treatments:
colforsin ( 3 ) , isoproterenol ( 3 )

References 

1

Beautrait A, et al. (2014) Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS. J Biol Chem 289, 25262-75
25049229   Curated Info

2

Ménard L, et al. (1997) Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization. Mol Pharmacol 51, 800-8
9145918   Curated Info

3

Ferguson SS, et al. (1995) Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1. J Biol Chem 270, 24782-9
7559596   Curated Info