Ser56
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Home > Phosphorylation Site Page: > Ser56  -  PRM2 (mouse)

Site Information
HHRHRRCsRKRLHRI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451411

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
oocyte ( 2 )

Upstream Regulation
Kinases, in vitro:
SRPK1 (mouse) ( 1 )
Putative upstream phosphatases:
PPP1CC iso2 (mouse) ( 2 )
Phosphatases, in vitro:
PPP1CC iso2 (mouse) ( 2 )

References 

1

Gou LT, et al. (2020) Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell 180, 1212-1227.e14
32169215   Curated Info

2

Itoh K, et al. (2019) Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal 12
30914484   Curated Info