Ser109
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Home > Phosphorylation Site Page: > Ser109  -  CLCN3 (human)

Site Information
ERHRRINsKKKESAW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451427

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
neuron-'brain, hippocampus' ( 1 ) , tsA (epithelial) ( 2 )

Upstream Regulation
Putative in vivo kinases:
CAMK2A (human) ( 1 )
Kinases, in vitro:
CAMK2A (human) ( 1 , 2 )

Downstream Regulation
Effects of modification on CLCN3:
activity, induced ( 1 ) , activity, inhibited ( 2 )
Effects of modification on biological processes:
neural plasticity ( 1 )

References 

1

Farmer LM, Le BN, Nelson DJ (2013) CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses. J Physiol 591, 1001-15
23165767   Curated Info

2

Robinson NC, et al. (2004) Identification of an N-terminal amino acid of the CLC-3 chloride channel critical in phosphorylation-dependent activation of a CaMKII-activated chloride current. J Physiol 556, 353-68
14754994   Curated Info