Thr645
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Home > Phosphorylation Site Page: > Thr645  -  STAT6 (mouse)

Site Information
GRGyVSTtIKMTVER   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451417

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
kidney ( 1 ) , lymphocyte ( 1 ) , macrophage-bone marrow ( 1 )

Upstream Regulation
Regulatory protein:
PPP2CA (human) ( 1 )
Treatments:
LPS ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 ) , cell motility, inhibited ( 1 ) , transcription, inhibited ( 1 )

References 

1

Liang Y, et al. (2021) PP2Acα promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNFα production. Cell Death Differ
33934104   Curated Info