Ser799
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Home > Phosphorylation Site Page: > Ser799  -  Rb (rat)

Site Information
PGGNIYIsPLKsPYK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447980

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , phospho-antibody ( 3 , 4 , 5 ) , western blotting ( 3 , 4 , 5 )
Relevant cell line - cell type - tissue:
astrocyte-'brain, cerebrum' ( 4 ) , glial ( 3 ) , thymus ( 1 ) , vascular smooth muscle cell ('muscle, smooth') ( 5 )

Upstream Regulation
Treatments:
5-HT ( 5 ) , BDNF ( 3 ) , CBX ( 4 ) , endothelin ( 4 ) , RANTES ( 3 ) , serum ( 5 ) , virus infection ( 3 )

References 

1

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

2

Park JH, Arakawa-Takeuchi S, Jinno S, Okayama H (2011) Rho-associated Kinase Connects a Cell Cycle-controlling Anchorage Signal to the Mammalian Target of Rapamycin Pathway. J Biol Chem 286, 23132-41
21561859   Curated Info

3

Akay C, et al. (2011) Site-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity. Mol Cell Neurosci 47, 154-65
21504794   Curated Info

4

Tabernero A, Sánchez-Alvarez R, Medina JM (2006) Increased levels of cyclins D1 and D3 after inhibition of gap junctional communication in astrocytes. J Neurochem 96, 973-82
16412096   Curated Info

5

Garnovskaya MN, et al. (2004) Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation. J Biol Chem 279, 24899-905
15069084   Curated Info