Ser369
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Home > Phosphorylation Site Page: > Ser369  -  RARA (mouse)

Site Information
YVRKRRPsRPHMFPK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451381

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 ) , phosphoamino acid analysis ( 2 ) , phosphopeptide mapping ( 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , F9 (testicular) ( 2 ) , lymphocyte [RARA (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKACA (mouse) ( 2 )
Kinases, in vitro:
PKACA (mouse) ( 2 )
Treatments:
As2O3 ( 1 ) , colforsin ( 2 ) , retinoic_acid ( 1 )

Downstream Regulation
Effects of modification on RARA:
activity, induced ( 2 ) , protein degradation ( 1 )

References 

1

Nasr R, et al. (2008) Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nat Med 14, 1333-42
19029980   Curated Info

2

Rochette-Egly C, et al. (1995) Phosphorylation of the retinoic acid receptor-alpha by protein kinase A. Mol Endocrinol 9, 860-71
7476969   Curated Info