Tyr24

Site Information
GGCCGSDyKQyVFGG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1270903

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 ) , MEF (fibroblast) ( 1 ) , PC-12 (chromaffin) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	cell motility, altered ( 1 ) , cytoskeletal reorganization ( 1 )

References
1	Neumann-Giesen C, Fernow I, Amaddii M, Tikkanen R (2007) Role of EGF-induced tyrosine phosphorylation of reggie-1/flotillin-2 in cell spreading and signaling to the actin cytoskeleton. J Cell Sci 120, 395-406 17213334 Curated Info