Thr139
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Home > Phosphorylation Site Page: > Thr139  -  PRMT5 (human)

Site Information
tNLARVLtNHIHtGH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1267669102

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
LKB1 (human) ( 1 )
Kinases, in vitro:
LKB1 (human) ( 1 )

Downstream Regulation
Effects of modification on PRMT5:
enzymatic activity, induced ( 1 )

References 

1

Lattouf H, et al. (2018) LKB1 regulates PRMT5 activity in breast cancer. Int J Cancer
30289978   Curated Info