Tyr325
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Home > Phosphorylation Site Page: > Tyr325  -  HDAC3 (human)

Site Information
AISEELPySEyFEyF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1267669100

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:
HCT116 (intestinal) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )

Downstream Regulation
Effects of modification on HDAC3:
activity, induced ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 )

References 

1

Seo J, et al. (2018) Tyrosine phosphorylation of HDAC3 by Src kinase mediates proliferation of HER2-positive breast cancer cells. J Cell Physiol 234
30317579   Curated Info

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