Thr370
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Home > Phosphorylation Site Page: > Thr370  -  CAPN2 (human)

Site Information
GNWRRGstAGGCRNY   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451304

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )
Kinases, in vitro:
PKACA (human) ( 1 )
Treatments:
8-Rp-cAMP ( 1 ) , cAMP_analog ( 1 ) , H-89 ( 1 )

Downstream Regulation
Effects of modification on CAPN2:
activity, inhibited ( 1 )
Effects of modification on biological processes:
cell motility, altered ( 1 )

References 

1

Shiraha H, et al. (2002) Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain. Mol Cell Biol 22, 2716-27
11909964   Curated Info