Thr483

Site Information
KHQGVSktQsLPVTE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 12673100

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	cervical cancer ( 2 ) , cervical adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 , 3 ) , HeLa S3 (cervical) ( 2 )

Upstream Regulation
Treatments:	nocodazole ( 2 )

References
1	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
2	Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3 20068231 Curated Info
3	Zhou J (2008) CST Curation Set: 4707; Year: 2008; Biosample/Treatment: cell line, HeLa/UV; Disease: cervical adenocarcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho(Ser/Thr) ATM/ATR Substrate Antibody (polyAB) Cat#: 3005, PTMScan(R) Phospho-ATM/ATR Substrate Motif (pS/pTQ) Immunoaffinity Beads Cat#: 1980 Curated Info