Lys154
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Home > Acetylation Site Page: > Lys154  -  p21Cip1 (human)

Site Information
MTDFyHskRrLIFSk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12615903

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 ) , trichostatin_A ( 1 )

Downstream Regulation
Effects of modification on p21Cip1:
molecular association, regulation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
carcinogenesis, inhibited ( 1 ) , cell cycle regulation ( 1 ) , cell growth, inhibited ( 1 )
Inhibit interaction with:
C8A (human) ( 1 )

References 

1

Li Z, et al. (2010) An HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis. Oncogene 29, 2659-71
20154723   Curated Info

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