Ser395
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Home > Phosphorylation Site Page: > Ser395  -  CASK (mouse)

Site Information
DKINTkSsPQIRNPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1261102

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mass spectrometry ( 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , CAD (neuron) ( 2 ) , COS (fibroblast) ( 2 ) , neuron:synaptosome-brain ( 2 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (mouse) ( 2 )
Kinases, in vitro:
CDK5 (human) ( 2 )
Treatments:
seliciclib ( 2 )

Downstream Regulation
Effects of modification on CASK:
intracellular localization ( 2 ) , molecular association, regulation ( 2 )
Inhibit interaction with:
liprin alpha 1 (mouse) ( 2 )

References 

1

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

2

Samuels BA, et al. (2007) Cdk5 Promotes Synaptogenesis by Regulating the Subcellular Distribution of the MAGUK Family Member CASK. Neuron 56, 823-837
18054859   Curated Info