Tyr1113
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Home > Phosphorylation Site Page: > Tyr1113  -  TIE1 (mouse)

Site Information
MLEARKAyVNMSLFE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451279

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Putative in vivo kinases:
TIE1 (mouse) ( 1 )
Kinases, in vitro:
TIE1 (mouse) ( 1 )
Treatments:
M-CSF ( 1 )

Downstream Regulation
Effects of modification on TIE1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )
Induce interaction with:
PIK3R1 (mouse) ( 1 )

References 

1

Kontos CD, Cha EH, York JD, Peters KG (2002) The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis. Mol Cell Biol 22, 1704-13
11865050   Curated Info

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