Tyr389
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Home > Phosphorylation Site Page: > Tyr389  -  RUFY1 (human)

Site Information
TKVELETykQTRQGL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451277

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 ) , mutation of modification site ( 3 ) , phospho-antibody ( 3 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 3 ) , Jurkat (T lymphocyte) ( 2 ) , skin ( 1 )

Upstream Regulation
Putative in vivo kinases:
Etk (human) ( 3 )

Downstream Regulation
Effects of modification on RUFY1:
intracellular localization ( 3 )

References 

1

Tucker M (2010) CST Curation Set: 9544; Year: 2010; Biosample/Treatment: tissue, skin/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

2

Guo A (2010) CST Curation Set: 9181; Year: 2010; Biosample/Treatment: cell line, Jurkat/pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Yang J, Kim O, Wu J, Qiu Y (2002) Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking. J Biol Chem 277, 30219-26
11877430   Curated Info