Thr21
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Home > Phosphorylation Site Page: > Thr21  -  BMAL1 (human)

Site Information
DFMsPGPtDLLSSSL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 12575204

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (human) ( 1 )
Kinases, in vitro:
GSK3B (human) ( 1 )

Downstream Regulation
Effects of modification on BMAL1:
protein degradation ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

Sahar S, et al. (2010) Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. PLoS One 5, e8561
20049328   Curated Info