Ser835

Site Information
VRSLRVDsEPVLVHC SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 451192

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 )
Disease tissue studied:	hepatocellular carcinoma, surrounding tissue ( 1 )
Relevant cell line - cell type - tissue:	hepatic-'liver, para-hepatocellular carcinoma tissue' ( 1 )

Downstream Regulation
Effects of modification on PTPN3:	molecular association, regulation ( 2 )
Induce interaction with:	14-3-3 beta (human) ( 2 )

References
1	Tucker M (2009) CST Curation Set: 6571; Year: 2009; Biosample/Treatment: liver, para-hepatocellular carcinoma tissue, hepatic/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
2	Zhang SH, et al. (1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein. J Biol Chem 272, 27281-7 9341175 Curated Info

References

Tucker M (2009) CST Curation Set: 6571; Year: 2009; Biosample/Treatment: liver, para-hepatocellular carcinoma tissue, hepatic/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

Zhang SH, et al. (1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein. J Biol Chem 272, 27281-7
9341175 Curated Info