Thr9
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Home > Phosphorylation Site Page: > Thr9  -  NKX2-1 (rat)

Site Information
SMSPKHTtPFsVSDI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 451108

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 , 2 ) , phosphopeptide mapping ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lung cancer ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACB (mouse) ( 2 )
Kinases, in vitro:
PKACA (rat) ( 2 ) , PKACB (mouse) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Feliciello A, et al. (2000) Thyroid transcription factor 1 phosphorylation is not required for protein kinase A-dependent transcription of the thyroglobulin promoter. Cell Growth Differ 11, 649-54
11149600   Curated Info

2

Yan C, Whitsett JA (1997) Protein kinase A activation of the surfactant protein B gene is mediated by phosphorylation of thyroid transcription factor 1. J Biol Chem 272, 17327-32
9211870   Curated Info